Abstract
Tachycardia and high troponin levels prognosticate for poor outcomes in human sepsis [1]. Reducing cardiac stress with beta-blockade has been proposed as an important therapeutic strategy as high catecholamine levels are injurious [2]. We have characterized a 72h fluid-resuscitated rat model of faecal peritonitis where prognostication can be made with high sensitivity and specificity at 6h from heart rate and stroke volume [3].
Highlights
Tachycardia and high troponin levels prognosticate for poor outcomes in human sepsis [1]
Reducing cardiac stress with beta-blockade has been proposed as an important therapeutic strategy as high catecholamine levels are injurious [2]
We have characterized a 72h fluid-resuscitated rat model of faecal peritonitis where prognostication can be made with high sensitivity and specificity at 6h from heart rate and stroke volume [3]
Summary
Tachycardia and high troponin levels prognosticate for poor outcomes in human sepsis [1]. Introduction Tachycardia and high troponin levels prognosticate for poor outcomes in human sepsis [1]. Reducing cardiac stress with beta-blockade has been proposed as an important therapeutic strategy as high catecholamine levels are injurious [2]. We have characterized a 72h fluid-resuscitated rat model of faecal peritonitis where prognostication can be made with high sensitivity and specificity at 6h from heart rate and stroke volume [3]. Objectives To determine whether non-survival is associated with early changes in troponin release and circulating catecholamine levels.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
