Abstract

Mid-urethral sling (MUS) surgery is successful in treating stress urinary incontinence in women. However, decreased sexual function, particularly lowered orgasm satisfaction, has been reported post-operatively. Previous work has demonstrated that MUS placement directly traverses through the periurethral space, impacting the tissue of this region. Evidence suggests that this female periurethral tissue (FPT) is composed of glandular structures, nerve fibers, and blood vessels. Our working hypothesis is that these glandular structures are involved in the female sexual response (FSR) such that they should contain both autonomic and sensory innervation, reflecting their role as a secretory tissue, as well as a tissue that may respond to arousal stimuli.

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