0725 PRESHYON: The Prevalence On The Risk Of Obstructive Sleep Apnea Among Patients With Uncontrolled Hypertension Seen At The Out-Patient Department Of The University Of The Philippines- Philippine General Hospital

Abstract

Abstract Introduction Obstructive Sleep Apnea (OSA) is a breathing disorder linked to increased morbidity and mortality, 1 and associated with decreased quality of life and functional impairment of daily living.2 OSA has been established to be associated with hypertension wherein the prevalence of OSA is 30%, 24,25 however, local prevalence has been lacking. The gold standard for OSA is polysomnography but this is expensive and has limited availability. Questionnaires provide risk stratification to determine if the patient needs further sleep evaluation. Recognition and treatment of OSA could lead to improving long term outcomes of patients with uncontrolled hypertension. 31-33 Methods This is a cross-sectional study that enrolled 325 adult Filipino HTN patients seen at the outpatient department (OPD) of UP-PGH from January 2019 to July 2019. Participants also answered Berlin Questionnaire (BQ), Epworth Sleepiness Scale (ESS) and the St. Lukes Medical Center-Obstructive Sleep Apnea Clinical Score (SLMC-OSACS) for their OSA risk. Descriptive statistics were used to summarize the clinical characteristics of the patients. Chi-square test was used to analyze categorical data univariately. Logistics regression analysis was used to determine the association of the different independent variable with the outcome (dependent) variable. Results The risk of OSA was significantly high among uncontrolled HTN patients: 106 (60.7%) based on BQ (p<0.0001) and 68 (69.4%) based on SLMC-OSACS (p<0.0001). OSA risk among uncontrolled HTN was 6x higher (OR=5.69; 95% CI=3.49-9.28;p<0.0001) using the BQ and 4x higher (OR=3.70; 95% CI=2.19 - 6.26;p=<0.0001) using the SLMC-OSACS than those with controlled HTN. Other variables significantly associated with high risk OSA were BMI and other comorbidities. Conclusion The risk of OSA was significantly high among uncontrolled HTN patients. In utilizing these sleep questionnaires and determining the risk for OSA among patients with uncontrolled hypertension will lead for early evaluation of OSA and complications. Locally this will aid in improving detection and provide a more strategic management of uncontrolled hypertension to decrease associated cardiovascular events. This will guide our clinicians to prioritize patients who would benefit referral to sleep specialists Support