0709 Chronotype characteristics in restless legs syndrome

Abstract

Abstract Introduction There are many people with a late chronotype in restless legs syndrome(RLS) patients. This phenomenon may be caused by sleep disturbance due to lower extremity symptoms of RLS, or it may be caused by some disease-specific characteristic of RLS, involving the circadian system. The aim of this study is to estimate the cause of this phenomenon. Methods This study is a retrospective study and was performed on 100 RLS patients without other major sleep disorders and 51 control subjects. Patients taking hypnotics such as benzodiazepines, melatonin, and zolpidem were also excluded. A survey on various sleep questionnaire scores was made for RLS patients. The questionnaire scores between the two groups were compared, and the collected data were analyzed with a significance level of 0.05. Results When the severity of RLS was evaluated by the IRLS score and the proportion of patients with late chronotype was checked by severity, it was 31.1% in the mild group, 41.7% in the moderate group, and 52.6% in the severe group(p=0.420). When the patient group with mild severity was compared with the entire patient group, the PSQI level was 82.0% of the total patient group(p=0.026). Conclusion RLS patients are more likely to have a late chronotype than those without RLS. The higher the severity of RLS symptoms, the higher the rate of having a late chronotype. Therefore, it could be inferred that the late chronotype identified in RLS patients was secondary to sleep disturbances caused by RLS symptoms. Support (if any)