Abstract
DNA methylation is one of major epigenetic mechanisms by which regulate a panel of gene expressions. An old but a revisiting compound, 5-azacytidine, is a pyrimidine nucleoside analog of cytidine that can inhibit DNA methyltransferase, induce cell differentiation, and has direct cytotoxicity on abnormal bone marrow hematopoietic cells. Thus, systemic administration of 5-azacytidine has been approved for the treatment of myelodysplastic syndrome and acute myeloid leukemia. However, the effect of topical 5-azacytidine on skin inflammation is largely unknown.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
