049 The risk factor of cervical spine involvements with psoriatic arthritis

Abstract

049 The risk factor of cervical spine involvements with psoriatic arthritis K Ikumi, S Kobayashi, N Tamura, H Inoue, E Nishida and A Morita 1 Geriatric and Environmental Dermatology, Nagoya City University, Nagoya, Japan, 2 Department of Rheumatology, Juntendo Koshigaya Hospital, Koshigaya, Japan, 3 Rheumatology, Juntendo University, Bunkyo-ku, Japan and 4 Orthopedic Surgery, Juntendo University, Bunkyo-ku, Japan The prevalence of psoriasis is 0.1% and psoriatic arthritis is 10% in Japan. In Western countries, 35% to 75% of PsA patients exhibit cervical spine involvement, but the frequency of cervical spine involvements in Asian patients is unknown. In addition, risk factors of that are not known. Here, we retrospectively analyzed clinical and radiologic informations of consecutive PsA patients who attended our hospital from 2010 to 2015. Patients who satisfied the following criteria were included: 1) Fulfilled CASPER criteria, 2) Used Biologics, 3) Presence of symptoms suggestive of axial joint involvements low back pain. Thirty-eight patients were included. Nineteen patients (50.0%) exhibited cervical spine involvements. Of the 38 patients, 4 (10.5%) were observed bridging osteoproliferations likely to DISH. In statics, serum CRP of cervical spine involvements’ existing group was higher than that of non-existing group (Mann-whitney U test: p<0.01). Furthermore, there was a correlation of cervical spine involvements with serum CRP. (Spearman’s rank correlation coefficient: correlation coefficient1⁄40.583, p < 0.01) In our study, cervical spine involvement was often observed in PsA patients, suggesting a similar frequency of cervical involvements between Asian countries and Western countries. In addition, increased rates of serum CRP was related to cervical spine involvements. Thus, regular examination of the cervical spine and serum CRP in PsA patients should be recommended. 050 Sense of coherence e is it a protective factor in chronic urticaria patients? A Ograczyk, Z Kabzinska, A Pietrzak and A Zalewska-Janowska Medical University of Lodz, Lodz, Poland Chronic urticaria is perceived by patients as an important source of stress which decreases significantly their quality of life (QoL). Sense of coherence (SOC) can be treated as an important resource in coping with disease demands and is believed to be a protective factor against anxiety and depression. The study aim was to estimate the relationships between SOC, depressive and anxiety symptoms, and QoL. The research group consisted of 46 females (age M1⁄444.6; SD1⁄414.2; range: 21-68 years). The average disease duration was 3.6 years (SD1⁄45.8 years; range: 6 months-25years). The psychological methods: Sense of Coherence Questionnaire (SOC, Antonovsky), Hospital Anxiety and Depression Scale (HADS, Zigmond, Snaith) and The Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL, Baiardini et al) were applied. The statistical significance was set at 0.05. The relations between depressive and anxiety symptoms, and dicreased QoL (dimensions swelling/mental state and sleep problems) were demonstrated. SOC and all its components negatively correlated with depressive and anxiety symptoms. The strongest relation was noted between manageability and anxiety (r1⁄4-0.65, p<0.001). SOC and its subscales also negatively correlated with QoL (the strongest link was observed between comprehensibility and domain swelling/mental state (r1⁄4-0.68, p<0.001). It is the evidence of SOC protective role. Based on the obtained results, it is worth employing psychological interventions for urticarial patients enhancing personal resources to improve their QoL.