Abstract

Background The association between elevated plasma coagulation factor VIII (FVIII) levels and Venous Thromboembolism (VTE) was first described in the Leiden Thrombophilia Study. Until today the measurement of FVIII levels is not included in laboratory investigation of possible congenital thrombophilia in cases of unexplained VTE. Nevertheless, FVIII levels above 150% seemed to be correlated with high risk of VTE.

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