0476 : Clinical characteristics and predictors of mortality at six months of patients hospitalized for acute heart failure

Abstract

Heart failure is known as a major cause of morbidity and mortality in developed countries. Few data are currently available on the demographic and clinical characteristics and prognosis of patients hospitalized for acute heart failure. To determine the clinical characteristics and predictors of 6- month mortality of patients admitted for acute heart failure. Retrospective Study on 234 patients hospitalized for acute heart failure. The demographic, clinical, echocardiographic and laboratory data were collected and tested by univariate and multi-variate studies to identify prognostic markers. The mean age was 65 ± 13.8 years, 65% were male. Hypertension was noted in 60.3% and 51.7% diabetes. 60.3% had a clinical congestive heart failure. The main causes of HF were ischemic heart disease (48.7%), Hypertension (21.4%) and dilated cardiomyopathy (14.5%). The precipitating factor most frequently noted was ischemic attack (35%) followed by pulmonary disease (20.5%). 97% of our patients had received transthoracic echocardiography, among them 46.6% had a normal ejection fraction and 17.2% had a severe left ventricular dysfunction. At the exit, the use of an inhibitor of the renin angiotensin system was observed in 86.8% and that of beta-blockers in 41.5% of patients. The mortality rate at 6 months was 11.2%. In multivariate analysis, independent predictors of mortality at 6 months were: QRS width > 130 ms, hyperglycemia on admission, higher HbA1C, worsening of renal function during the stay and non-use of beta-blockers to the output. The predictive prognostic factors for mortality in the medium and long ermes are still poorly studied. In our study, independent predictors of mortality at 6 months were: wide QRS > 130 ms, hyperglycemia on admission, a high A1C, worsening of renal function during the hospitalization and non-use of beta-blockers on exit. The author hereby declares no conflict of interest