Abstract
About half of American adults use dietary supplements, primarily because they believe that supplements promote overall health and prevent disease. Many use chromium-containing supplements in the belief that they are effective in stabilizing blood glucose levels, lowering plasma lipids, moderating mood and cognitive function, and reducing biomarkers of oxidative stress and inflammation. However, the evidence to support such effects is variable. Most of the randomized controlled trials in the scientific literature have used a range of chromium formulations, in doses typically between 200 and 1000 μg/day primarily in type 2 diabetics and individuals with polycystic ovary syndrome. They are small in number, short in duration, and have yielded mixed results. Some data suggests that efficacy may vary depending on the chromium formulation, dose, and duration of use. For these reasons, chromium-containing supplements to prevent or treat these conditions have not been endorsed by the guidelines of authoritative scientific bodies.
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