Abstract
of the study was to evaluate the possible existence of a nightmare modulation of VTCL stability in ICD recipients. We evaluated 45 ICD pts with 104VT episodes occurred both at day (80) and night (24) time in a FU period of 5±3years. As index of VTCL stability we considered the coefficient of variance (CVRR=SD/Mean RRX100) of the last 5-10 consecutive stored normal RR intervals prior to the VT. During day-night, the VTCL was 340±29ms and 352±45ms (p=NS) and the CVRR was 2,83±0,52 and 3,36±0,68(p=0.017). The VTCL is less stable during night compared to the day time, in pts with DCM. A possible explanation is that, the sympathovagal nightmare alteration modifies the electrophysiological properties of the arrhythmogenic substrate. The clinical significance of this study is towards programming the ICD parameters.
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