Abstract
Autoimmune blistering diseases (AIBDs), mainly including epidermolysis bullosa acquisita (EBA), pemphigus Vulgaris (PV) and bullous pemphigoid (BP), are a large class of autoimmune diseases presenting the blistering eruptions on the skin and mucosa membrane. Circulating autoantibodies play a critical role in the pathogenesis, antibody-specific B cells and CD4+T cells involved as well. While vitiligo, a common pigmentation disorder, is mostly considered as CD8+T cell-mediated, with multiple melanocyte-derived autoantibodies also detectable in part of the patients, although its pathogenicity remains undetermined.
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