0332 Objective and subjective sleep quality in Mexican Americans and non-Hispanic Whites: the HABLE-Dormir Study

Abstract

Abstract Introduction The ongoing prospective Health & Aging Brain among Latino Elders (HABLE)-Dormir Study is designed to investigate the association between objective and subjective sleep quality and cognitive impairment among Mexican Americans and non-Hispanic Whites (NHWs). Methods We plan to recruit 1000 community-dwelling Mexican Americans and NHWs and elders (age 50 and above). Objective sleep duration and fragmentation were assessed by 7-day wrist actigraphy; presence of sleep disordered breathing (SDB) was determined using WatchPAT; and subjective sleep quality and excessive daytime sleepiness (EDS) were examined by Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS), respectively. Results To date, 367 participants have been enrolled (62% women, 45% Mexican Americans, mean age 67.3±8.4 years); 296 (81%) of the participants had normal cognition, 56 (15%) had mild cognitive impairment (MCI), and 15 (4%) had dementia. On average, participants had a mean sleep duration of 7.3±1.1 hours, sleep efficiency of 88.3±5.3%, and wake after sleep onset (WASO) of 55.2±29.3 minutes. Almost half (51%) of the participants had moderate to severe SDB defined by WatchPAT-derived respiratory event index (REI) >=15, 54% had self-reported poor sleep quality (PSQI>5), and 10% reported EDS (ESS>=11). After adjustment for age, Mexican Americans had lower sleep efficiency (86.5% vs. 89.5%, p<0.001) and greater WASO (63.6 vs. 48.9 minutes, p<0.001), compared to NHWs. Sleep duration did not differ significantly among NHWs (7.2 hours) and Mexican Americans (7.4 hours); p=0.20. The prevalence of moderate to severe SDB was similar in NHWs (51.2%) and Mexican Americans (50.0%); p=0.84. Besides, NHWs and Mexican Americans had similar PSQI and prevalence of EDS. Conclusion In this initial analysis, Mexican Americans have worse objective sleep quality, but similar sleep duration, prevalence of SDB and subjective sleep quality as compared to NHWs. Continued investigations are needed to explore potential racial/ethnic disparities in sleep health and how differences in objective and subjective measurements vary by race and ethnicity. Support (If Any)