Abstract
Although clinical studies of the high-flow nasal cannula (HFNC) and its effect on positive end-expiratory pressure (PEEP) have been performed, the mechanism of the washout effect and its relation with HFNC flow have not been well evaluated. Therefore, we made a respiratory model that can exhale with controllable end-tidal PCO2 (PETCO2) to evaluate the washout effect of HFNC.Objective. To evaluate the quantitative results of HFNC's washout effect comparing open- and closed-mouth models.
Highlights
Clinical studies of the high-flow nasal cannula (HFNC) and its effect on positive end-expiratory pressure (PEEP) have been performed, the mechanism of the washout effect and its relation with HFNC flow have not been well evaluated
we made a respiratory model that can exhale with controllable end-tidal PCO2
The artificial respiratory model consisted of a lung model
Summary
Clinical studies of the high-flow nasal cannula (HFNC) and its effect on positive end-expiratory pressure (PEEP) have been performed, the mechanism of the washout effect and its relation with HFNC flow have not been well evaluated. We made a respiratory model that can exhale with controllable end-tidal PCO2 (PETCO2) to evaluate the washout effect of HFNC.Objective. To evaluate the quantitative results of HFNC’s washout effect comparing open- and closed-mouth models
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