Abstract
In a previously published study of the brain activity unique to orgasm in women, brain activity at orgasm (self- and partner-induced) was compared with that at onset of genital stimulation, immediately before onset of orgasm, and immediately after cessation of orgasm in a sample of 10 female participants. Brain activity gradually increased leading up to orgasm, peaked at orgasm, and then decreased. Activated brain regions included sensory, motor, reward, frontal cortical, and brainstem regions (e.g., nucleus accumbens, insula, anterior cingulate cortex, orbitofrontal cortex, operculum, right angular gyrus, paracentral lobule, cerebellum, hippocampus, amygdala, hypothalamus, ventral tegmental area, and dorsal raphe). We presently report data based on 20 orgasms, doubled from the previous 10.
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