019 Evaluation of Patient-report Outcomes (PROs), Medical and Patient Characteristics of Colorectal/Anal Cancer Patients/Survivors

Abstract

To evaluate patient-reported outcomes (PROs) and medical and patient characteristics of colorectal/anal cancer patients/survivors at the Female Sexual Medicine & Women’s Health Program (FSMWHP) at Memorial Sloan Kettering Cancer Center. A limited waiver of authorization was obtained for this retrospective study. Ninety-nine women with a history of colon, rectal or anal cancer were seen for an initial consult at the FSMWHP from 01/12–07/17. Data were collected using the FSMWHP Clinic Assessment Form, which includes the Vaginal Assessment Scale (VAS), Vulvar Assessment Scale (VuAS), vulvovaginal/sexual health promotion strategies, pelvic exam checklist, PROs (Female Sexual Function Index [FSFI] and Sexual Activity Questionnaire [SAQ]), and exploratory items. Descriptive statistics for our data analysis were calculated using SPSS. The sample consisted of patients with colon (n=9), rectal (n=49), or anal cancer (n=41) diagnosed between 1989-2015. Mean age was 48 years (range, 18-77). On average, patients were seen 3 years from diagnosis (range, 9 months–9.5 years). Sixty-seven percent (56/83) had mild-severe vaginal dryness; 36% (30/84) mild-severe dyspareunia (VAS); and 60% (44/73) mild-severe vulvar dryness (VuAS). On exam, 54% (30/56) had mild-severe vaginal atrophy. Forty percent (21/54) had fecal incontinence; 47%(27/58) urinary incontinence; 56% (32/57) currently used pads; and 67% (44/66) had pain with exam. Thirty-three percent reported current sexual activity. The primary reason for not engaging in sexual activity (SAQ) was a physical issue making sex difficult or uncomfortable (54%). In all, 98% (88/90) scored <26.6 on the FSFI (mean, 10.5; median, 8.0), indicating female sexual dysfunction; 48% (39/82) were not confident about future sexual activity.