Abstract

Background: In children and adolescents, growth hormone (GH) therapy requires a long-term commitment to daily subcutaneous injections. Improvements in device delivery methods have been made, including injection pens, autoinjector pens, and needle-free delivery devices. Because of the requirement for daily injections, patient acceptance of devices is important. Developments that improve patient acceptance will likely increase compliance with GH therapy. A novel electronic injection delivery device (e-device) that allows for physician programmed preset dosing, cartridge alarms, and injection monitoring is now available. A user trial, evaluating the performance and handling of this device among subjects, nurses, and physicians, is described.

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