0134 Self-Reported Sleep is Associated with Central, But Not Peripheral Blood Pressure Values in Healthy Children

Abstract

Abstract Introduction Shortened and poor quality sleep have emerged as nontraditional risk factors for the development of high blood pressure (BP) in adults, but it is unclear if these relations exist in younger children. Self-report and objective sleep measurements are both clinically relevant and may inform interventions to improve sleep in this population, but do not always coincide with one another. The purpose of this study was to evaluate both self-reported and objective sleep metrics and their associations with central and peripheral BP values in younger children. Methods Participants included 21 healthy 7-12-year-old children (10±0.5 yrs, 10M/11F). Self-reported sleep was evaluated using the Children’s Sleep Health Questionnaire and a total sleep score was generated, where a higher score indicates worse sleep (a score >41 indicates a pediatric sleep disorder). Objective sleep was recorded for 7 consecutive days and nights outside of the laboratory via wrist accelerometry and reported as sleep duration (SD) and sleep efficiency (SE). Following sleep monitoring, peripheral BP was measured and using pulse wave analysis (PWA) central BP was estimated, both of which were averaged over 3 trials. Pearson’s r correlations were used to assess relations between self-reported sleep score, objective sleep metrics, and BP values. Significance was set at p<0.05. Results Self-reported sleep score averaged 40±1 points, objective SD averaged 7.9±0.1 hours/night, and SE averaged 82±2%. Sleep score was significantly associated with central systolic and diastolic BP (r = .485, p = 0.03, and r = .517, p = 0.02, respectively), but not peripheral BP values. Objective SD and SE were not significantly associated with central or peripheral BP values. Conclusion In this sample, self-reported sleep score, but not objective sleep metrics, was associated with higher central BP values in healthy children age 7–12. Support Provided in part by P20GM113125.