0.1% Indomethacin眼藥水用於白內障手術之效應

Abstract

Indomethacin is a non-steroid anti-inflammatory agent, it has both anti-inflammatory and antiprostaglandin effect. It was suggested before that topical use of Indomethacin might prevent intraoperative miosis and transient postopreative ocular hypertenstion. It may reduce postoperative inflammation and corneal edema, too. So we designed the following study to evaluate the topical use of 0.1% Indomethacin eyedrops on cataract surgery. We collected 30 cataract eyes, 20 eyes belong to the study group and 10 eyes in the control group. In addition to the routine preoperative and postoperative medications, the eyes in the study group received 0.1% Indomethacin eyedrops from one day before surgery until two weeks after surgery. The eyes in the control group received routine preoperative and postoperative medications only. The results reveal that topical use of 0.1% Indomethacin eyedrops prevented intraoperative miosis, reduced postoperative anterior chamber reaction and promoted early recovery of postoperative corneal edema. But the intraocular pressure of the two groups showed no statistical significant difference.