0055 Physiological Based Predictive Models of Vigilance

Abstract

Abstract Introduction The Naval Submarine Medical Research Laboratory (NSMRL) is developing predictive models to examine how non-invasive, non-disruptive physiological monitoring can be used to track performance decrements due to sleep deficiency. Utilizing biometrics extracted from physiological measures to track performance changes would allow for automated tracking of fatigue and alleviate the overhead necessary to monitor individual schedules and sleep patterns. Methods NSMRL collaborated with the University of Connecticut to run a sleep deprivation study that deprived 20 participants of sleep for a period of up to 25 hours. During this time, subjects completed multiple tasks, including the Psychomotor Vigilance Test (PVT) every few hours. A non-invasive monitoring system collected physiological data from participants, which includes eye tracking, electrocardiography, electrodermal activity, and facial tracking (e.g., blink metrics, heart rate variability, skin conductance levels, facial action units). Using this multimodal approach, biometrics were extracted and evaluated to determine their predictive power on PVT performance. Multiple linear regression, using predictors selected via sequential forward selection, was used to develop a model of performance at an individual level based on a subset of these metrics chosen using principal component regression. Results Thirty-eight biometrics were extracted from the collected data and used to produce a predictive model of PVT performance. Sequential forward selection was used to select 11 primary biometrics. The criteria for primary metric inclusion in the model was minimization of root mean squared error. The resultant model had a correlation coefficient (r) of 0.71 (p < 0.001) with a root mean squared error (RMSE) of 49.8 ms between the predicted reaction time and true reaction time for each subject. Conclusion Non-invasive, non-disruptive monitoring could be used to track individual cognitive performance decrement due to sleep deficiency. This study examined the capability of combining the data from four physiological monitors that can be contained within a wrist worn device and a desk or helmet mounted camera. Utilizing 11 biometrics obtained from these monitors a stepwise regression model was developed that significantly correlates with PVT reaction time at both an individual and group level. Support This work was supported by the Military Operational Medicine Research Program.