Abstract

Rapid prototyping was used to design and develop a three-dimensional (3D) scaffold for tissue engineering application. In this study, the nozzle guide (TB-CP-HN, MUSASHI ENGINEERING, INC., JAPAN) used with the syringe of the polymer deposition system (PDS) was evaluated by measuring the scaffold line width and height. 3D scaffolds were fabricated using a biodegradable polymer called poly-caprolactone (PCL). The PCL polymer can be deposited from the needle of a syringe using a 200- precision nozzle, at a pressure of 600 kPa and temperature of . The advantages and improvements in this nozzle guide were addressed through washer scaffold fabrication. Overall, this research indicated that the fabrication of a complex-shaped scaffold using an enhanced polymer deposition system may have potential for tissue engineering.

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