Abstract

The development of macular edema in neovascular age-related macular degeneration, diabetic retinopathy, retinal vein occlusion and in many other diseases, often causes significant visual deterioration and blindness, including in people of working age. One of the methods used of treating these diseases is the intravitreal administration of anti-VEGF drugs, including ranibizumab, aflibercept, brolucizumab, etc. Faricimab is a new drug that affects both vascular endothelial growth factor and angiopoietins. In order to reduce the frequency of intravitreal injections and prolong the time of the drug effect, sustained-release devices have been developed: Port Delivery System and biodegradable drugs. Keywords: diseases of the retina, macular edema, vascular endothelial growth factor, angiopoietins, anti-VEGF drugs

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