Abstract
Parkinson’s disease (PD) is the second most common neurodegenerative disease, with the prevalence of approximately 1% at age >60 years and 4% at age >80 years worldwide (1,2). The major pathological findings in PD are the progressive loss of dopaminergic neurons in the substantia nigra pars compacta and the presence of intraneuronal inclusions, Lewy bodies (3). Clinically, PD is characterized by motor symptoms, including bradykinesia, rigidity, resting tremor, and postural instability (4). PD is also associated with a high incidence of various non-motor symptoms, such as hyposmia, constipation, sleep problems, dysautonomia and psychological symptoms (4,5).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
