Abstract
Objectives. Gastric cancer is one of the leading causes of death in Taiwan and Solanum nigrum is one of the medicinal plants used in cancer therapy. However, there is no available information that addresses the mechanism by which Solanum nigrum affects human stomach cancer cells. Methods. We examined the dose effect of crude Solanum nigrum extract on the degree of N-acetylation of 2-aminofluorene (2-AF) in SC-M1 cell cytosol and intact cell cultures by acetyl Co-A recycling mixture assay and high pressure liquid chromatography (HPLC). Results. The crude extract of Solanum nigrum reducesed NAT activity in SC-M1 cytosol and intact cell cultures. Conclusions. Solanum nigrum affects malignant diseases by reducing NAT activity in SC-M1 cells.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
