КЛИНИЧЕСКИЕ И ЦИТОЛОГИЧЕСКИЕ ОСОБЕННОСТИ СТОМАТОЛОГИЧЕСКИХ ПРОЯВЛЕНИЙ НОВОЙ КОРОНАВИРУСНОЙ ИНФЕКЦИИ SARS-COV-2 У ПАЦИЕНТОВ СТАРШИХ ВОЗРАСТНЫХ ГРУПП

Abstract

Subject. Clinical and cytological manifestations of a new coronavirus infection in the oral cavity.
 Objectives. Identification, description and systematization of the main clinical and laboratory manifestations of a new coronavirus infection in the oral cavity in older patients.
 Methodology. The clinical study involved 50 elderly (60–74 years old) and senile (75–90 years old) patients who visited a dentist after an infection from September 2020 to February 2022. Study group 1 included patients with dystrophic syndrome, study group 2 – with inflammatory periodontal syndrome, study group 3 – with occlusive syndrome. Patients underwent dental and general clinical examination. The cytological study included an assessment of the cytoplasmic and karyological abnormalities level, calculating the integral indices of the buccal cytogram.
 Results. Most often, dental manifestations of a new coronavirus infection occur in older patients. All manifestations in the oral cavity are nonspecific, and the pathognomonic syndrome has not been established. The most common clinical manifestations are candidiasis, exacerbation of chronic periodontitis, exacerbation of herpes infection, etc. The cytological changes in the buccal epithelium reflect a general trend towards an increase in degenerative-dystrophic changes in cells, the predominance of apoptosis processes.
 Conclusion. Patients with dystrophic syndrome showed the greatest polymorphism of clinical manifestations associated with a new coronavirus infection (candidiasis in 59%, exacerbation of herpes infection in 47% of patients). In patients with inflammatory periodontal syndrome, exacerbation of chronic periodontitis was noted in 100% of cases. In patients with occlusive syndrome, there is an aggravation of the teeth hyperesthesia. Analysis of the integral indices of the buccal cytogram showed signs of accumulation of cytogenetic disorders after the infection.