이중가닥 RNA를 이용한 재래꿀벌 낭충봉아부패병 바이러스 질병 치료제의 과거와 현재

Abstract

Apiculture has been taking an important role for agriculture to provide the pollinators. In Korea, the major pollinators for agricultural and horticultural production are the Western honeybee ( Apis mellifera) and the Asian honeybee ( Apis cerana). Until late 2000s, the Asian honeybee has been responsible for 20% of the Korean apiculture, however, the majority of the Asian honeybee population was decimated by the sacbrood virus (SBV). In the meantime, molecular technologies have been developed to diagnose the SBV infected honeybees and to suppress the SBV by the RNA interference techniques. Recently, the industrialization of double-stranded RNA (dsRNA) as SBV inhibitor is at hand by virtue of the technological progress. This review article is to summarize the numerous efforts of the last decade to overcome the threats of SBV outbreak to protect Asian honeybees in Korea.