Abstract
The bioavailability of coenzyme Q10 (CoQ10) in various pharmaceutical formulations (solutions and tablets) containing solubilized CoQ10 in comparison to the lipophilic powder of CoQ10 has been studied in rats. It is established that the bioavailability of solubilised CoQ10 in tablets and solution after peroral administration is higher than that of lipophylic CoQ10 powder. The solution of a solubilised form ensured a shorter time of reaching the peak CoQ10 concentrations in plasma. Auxiliary swelling substances in tablets prolong and increase the absorption of CoQ10.
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