À propos de l’article : « L’élévation du taux de césariennes : un progrès nécessaire de l’obstétrique moderne » par P. Rozenberg. J. Gynecol Obstet Biol Reprod 2004 ; 33 : 279-89

Abstract

The use of palladium in organic synthesis has undergone a remarkable expansion in recent years. Many versatile synthetic methods have been developed and palladium is now the transition metal most frequently used in organic transformations. The reason for this rich chemistry is that palladium is highly efficient in almost all fundamental organometallic reactions, particularly those involving activation of organic substrates, and those leading to formation of new carbon–carbon and carbon–heteroatom bonds. This chapter focuses on the use of palladium-catalyzed reactions in the synthesis of alkaloids, but a few examples where palladium is used in stoichiometric amounts have also been presented in the chapter. The chapter describes a number of palladium-catalyzed processes that are often used in organic synthesis. These techniques can be conveniently divided into palladium(O) and palladium(II)-catalyzed reactions. In palladium(O)-catalyzed reactions the zerovalent metal is stabilized by ligands, most commonly by tertiary phosphines. Several different types of Pd(O)-catalyzed reactions are described in the chapter.