Abstract

Hamartomatous polyp with the same histopathological features as those of intestinal polyp associated with Peutz-Jeghers (P-J) syndrome without dermal mucosal pigmentation or family history (heredity) is considered as incomplete type of P-J syndrome. We encountered a case of hamartomatous polyp of jejunum, in which endoscopic tumor resection was effective for both diagnosis and treatment. The case was a 24-year-old man referred from his neighbouring physician under the suspicion of digestive tracthemorrhage because of dark-brown stool. On admission, test results disclosed mild anemia, but no other abnormalities, such as positive tumor markers, etc. In his medical or family history, there was no pigmentation of the dermal mucosa or polyp of the digestive tract. Because of the absence of lesions suspected of hemorrhage at endoscopic examination of the upper and lower digestive tract, the small intestine was examined under radiographic study and endoscopy. As a result, a single pedunculated polyp, which was measured about 30mm in diameter and had a slightly-redded head with dendritic surface, was detected about 10mm caudally to the ligament of Treitz, and this polyp was endoscopically resected. Histologically, this polyp was diagnosed as hamartoma of jejunum, in which branches of the lamina muscularis mucosa grew inward to the polyp in the dendritic form and were covered with hyperplastic mucosa without heteromorphism.

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