Abstract

本文提供一種快速的純化老鼠干擾素方法,用此法所得到的干擾素很穩定,比活性(Specific activity)為2.1×10^(6)單位/毫克蛋白質,而尖峯部份(peak fraction)的比活性則為5.7×10^(6)單位/毫克蛋白質,為粗干擾素(crude interferon)的438倍,整個純化過程需時才二天,因此我們相信應用毛孔玻璃色譜(Controlled Pore Glass Chromatography)和高效能液相層析分析色譜(High Performance Liquid Chromatography)將是一種快速且有效的純化方法。

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