Abstract

We evaluated the efficacy of supplements treatment (L-carnitine and melatonin) and low reactive level laser therapy (LLLT) and the integrated medicine program for IVF failures. After L-carnitine treatment blastocyst rate was significantly increased (37.0 % vs 60.8 %, P<0.01). After melatonin treatment good embryo rate (45.2 % vs 63.0 %, P<0.01), blastocyst rate (28.3 % vs 54.4 %, P<0.01) and good blastocyst rate (29.4 % vs 67.7 %, P<0.05) were significantly increased. After LLLT, the numbers of MII oocytes (1.7 vs 2.0, P<0.05) and the numbers of fertilized oocytes (1.6 vs 1.8, P<0.05) were significantly increased. Good embryo rate was significantly increased (64.0 % vs 79.0 %, P<0.05). In hormone supplemented frozen thawed ET cycles, pregnancy rate of day 3 embryos was significantly increased (6.7 % vs 17.8 %, P<0.05) after LLLT. And after the integrated medicine program, pregnancy rate was significantly increased (12.0 % vs 23.7 %, P<0.01).

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