心脳卒中および虚血性心脳症の病理学的研究 (IV)

Abstract

Cardiocerebral apoplexy is nowadays applied to a paticular case of myocardial infarction with cerebrovascular accident. For clarifing the pathogenesis of this syndrome, it is mandatory to investigate cardiac lesions in cases of cerebrovascular diseases and also cerebral lesions in cases of cardiovascural diseases. In our previous paper related to cardiac lesions, it was shown that there is marked complication of myocardial infarction or marked myocardial fibrosis in cases of cerebral infarction. This result suggest the morphological evidence for the existence of “Ischemic Cardioencephalopathy”. And it also suggests the existence of multi-foci ischemic lesions which are wide spread various visceral organs.With regard to this problem we observed renal lesions in 32 cases of cerebral infarction and 26 cases of cerebral hemorrhage. The results obtained were as follows.1) ischemic changes such as micro-subcortical infarctions and sclerotic changes of arcuate artery are more marked in cases of cerebral infarction than in that of cerebral hemorrhage.2) There are marked micro-subcortical infarction in all cases of cerebral infarction with myocardial infarction, and in 70% of cases of cerebral infarction with marked myocardial fibrosis.The correlation of ischemic lesions in kidney and heart is noteworthy.