Abstract

By the paper chromatography, we found that the water extracts of Digenia simplex Ag. contained a certain organic acid. We obtained this acid as the sodium salt, and isolated the free acid from this salt by means of ion-exchange resin. The sodium salt of this acid was identified by the rotation measurement, hydrolysis and elementary analysis as scdinm α-(α-D-mannostdo)-D-glycerate. By CRIEGEE's reaction, it was confirmed that mannose combined with α-hydroxyl of glyceric acid in this substance. From the results of pharmacological experiments with 0.1% aqueous solution of sodium α-(α-D-mannosido)-D-glycerate against Ascaris lumbrcorldes, it was found that Ascaris lumb. showed a characteristic struggling motion to escape.

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