β-Dimethylaminoethyl Benzhydryl EtherとChlorophenol誘導体の作る化合物について

Abstract

Formation of a molecular compound between several kinds of chlorophenol derivatives and β-dimethylaminoethyl benzhydryl ether (I) was examined by plotting a fusion curve by thermal analysis. It was thereby found that molecular compounds were formed from 2, 2′-thio-bis (4-chlorophenol) (II), 2, 2′-thio-bis (4, 6-dichlorophenol) (III), and 5-chlorosalicylic acid (IV) with the respective melting points of 92-95°, 120°, and 87°. It was also confirmed that the molecular compounds (X) and (XI) were formed respectively from (II) and (I), and (III) and (I) in 1:1 ratio only and not in 1:2 ratio. Further, the adduct (IX) of p-chloro-o-benzylphenol (VIII) and (I) was not obtained in a crystalline form but its formation was confirmed by its infrared by its infrared absorption spectral measurement.