고실내 덱사메타손(Dexamethasone) 주입술로 호전된 난치성 이루를 동반한 호산구성 중이염 : 사례 연구

Abstract

Eosinophilic otitis media (EOM) is a newly recognized intractable middle ear disease, characterized by a highly viscous otorrhea and an accumulation of eosinophils in middle ear effusion and middle ear mucosa. Since EOM can cause gradual or sudden deterioration of hearing, it is important to properly diagnose EOM. Systemic or topical steroid administration is known as the most effective treatment for patients with EOM ; however, oral steroid therapy has the potential to cause adverse drug effects. Recently, we experienced two cases of EOM that were given intratympanic dexamethasone injection had improvement in otologic symptoms including otorrhea and hearing loss. The instillation of dexamethasone into the middle ear cavity is noninvasive and effective treatment for controlling eosinophilic inflammation in this report. Identification of the characteristic manifestations of EOM, and the consequent definite diagnosis and an adequate treatment for EOM can help prevent sensorineural hearing loss in early stage. (J Clinical Otolaryngol 2016;27:306–315)