Обеспеченность витамином D детей с бронхиальной астмой города Красноярска в различные сезоны года

Abstract

Objective. To study the vitamin D availability of patients with bronchial asthma in different seasons of the year, depending on the severity, level of control over the disease, frequent ARVI, gender and age. Patients and methods. A comparative analysis of vitamin D provision in 187 patients with bronchial asthma in different seasons of the year, depending on the severity, level of control over the disease, frequent acute respiratory viral infections, gender and age, was carried out Results. Average vitamin D levels were normally recorded only in summer, and the lowest – in autumn and winter. In patients with mild asthma, vitamin D levels were significantly higher than in moderate and severe severity in all seasons of the year. With complete control of the disease, significantly higher levels of vitamin D were observed than in the absence of it also in all seasons. Vitamin D deficiency is more often registered in patients with a frequency of acute respiratory viral infections more than 6 times a year in autumn (p = 0.0410), winter (p = 0.0003) and spring (p = 0.0001); in girls in autumn (p = 0.0389), and in boys in winter and spring (p = 0.0311, p = 0.0388); in adolescents in autumn (p = 0.0289), winter (p = 0.0321) and spring (p = 0.0391). Conclusion. Vitamin D deficiency was significantly more often recorded in moderate and severe the course of asthma, in the absence of disease control, frequent acute respiratory infections, in adolescents, especially in seasons with low levels of insolation; in girls – in autumn, and in boys – in winter and spring. Key words: bronchial asthma, children, vitamin D, climatic seasons