Влияние COVID-19 на спермиологические показатели у мужчин репродуктивного возраста

Abstract

Introduction: The new coronavirus infection is dangerous not only in the acute period of the disease, but also during the period of convalescence, causing various complications. The long-term effects of the SARS-CoV 2 virus on male reproductive function are an important prognostic factor requiring comprehensive study. Purpose of the study: to study the long-term results of the impact of COVID-19 mild to moderate severity on spermological indicators in men of reproductive age. Materials and Methods: the study included 14 healthy men of reproductive age who were not vaccinated against COVID 19, who had negative results of an STI examination, normal spermological parameters, TUNEL test values <15%, who subsequently suffered a viral infection caused by the SARS-CoV 2 virus of mild and moderate severity, with persistent negative results of an STI examination. Results: а comparative analysis of the results of spermograms of patients before and after COVID 19 showed that the total number of spermatozoa before and after the disease (422.5 ± 53.9 and 410.2 ± 176.9 million, respectively), the indicator of the number of spermatozoa with progressive translational (PR) mobility (56.4 ± 8.7 and 54.4 ± 8.0%, respectively), morphologically normal male gametes before and after 3 months after COVID-19 (21.2 ± 4.3 and 20.2 ± 3.6%, respectively) are comparable. Normozoospermia was observed in all cases, TUNEL test values <15%. Conclusion: in the conducted study, mild and moderate COVID-19 did not have a clinically significant effect on the spermological parameters of men 3 months after COVID-19. Keywords: COVID-19, SARS-CoV 2 virus, spermological indicators, TUNEL-test.