Abstract
In this study, we investigated the antioxidant activities, alcohol metabolizing activities, nitrite scavenging ability, angiotensin converting enzyme (ACE), and elastase inhibitory effects of hot water extract from Makgeoly (HWM). Antioxidant activities were measured by using 2,2 diphenyl 1 picryl hydrazyl (DPPH) free radical scavenging activity and SOD (superoxide dismutase) like activity. The DPPH radical scavenging activity and SOD like activity of HWM were remarkably increased in a dose dependent manner and were 48.0% and 98.7% at 10 ㎎/㎖, respectively. To determine the influence of HWM on alcohol metabolizing activity, the generating activities of reduced nicotinamide adenine dinucleotide (NADH) by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) were measured. The facilitating rates of ADH and ALDH activity by HWM were remarkably increased in a dose dependent manner and were 70.2% and 64.1% at 10 ㎎/㎖, respectively. The inhibitory activity against angiotensin converting enzyme (ACE) of HWM was increased in a dose dependent manner and was 74.2% at 10 ㎎/㎖. The nitrite scavenging ability of HWM showed the most remarkable effect at pH 1.2 and 2 ㎎/㎖. These results indicated that HWM may have valuable biological properties owing to their antioxidant activities, ADH and ALDH activity, nitrite scavenging ability, and ACE inhibitory activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.