Abstract
3-Hydroxykynurenine is found to be abnormally accumulated in the body fluid of a silkworm mutant called “Aka-Aka” (rb) which we. have discovered. This abnormal accumulation in rb is caused by the inhibition of the metabolic courses in the normal silkworm, i.e. from kynurenine to anthranilic acid and from 3-hydroxykynurenine to 3-hydroxyanthranilic acid. It may therefore be concluded, that the rb gene controls kynureninase, which has relation to this metabolism.
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