Abstract
2-[2-(5-Nitro-2-furyl)vinyl]-2-imidazoline (VI) was prepared by the following route. Reaction of ethyl 3-(5-nitro-2-furyl) acrylimidate (IV) with ethylene diammonium bis-p-toluenesulfonate gave 2-[2-(5-nitro-2-furyl)vinyl]-2-imidazoline p-toluenesulfonate (V) in good yield, which was treated with cold sodium hydroxide solution to separate the free amine (VI). Antimicrobial activities of these nitrofuran compounds were tested.
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