Abstract

Currently, three main problems have been updated in gerontology and geriatrics: the first “early” is osteoporosis, the second “late” is Alzheimer’s disease, and the third “doubled” (comorbid, combined) is the presence of two diseases: Alzheimer’s disease and osteoporosis. The bone, in addition to mechanical and protective function, serves as a custodian of bone marrow cells and an organ for regulating the homeostasis of calcium ions. In the circadian gerontological period, osteoblasts, osteoclasts and osteocytes are determined by their respective functions of bone formation and bone resorption, and in the clinical-geriatric period of bone aging, bones and bone cells will change. 5P medicine and 5G medical services, new generation sequencing and pharmacogenetics are new modern foundations (paradigms) of personalized medicine — a key basis for understanding the common mechanisms of the pathogenesis of osteoporosis and Alzheimer’s disease. The presence of multiple chronic conditions in gerontology and geriatrics requires the use and clinical application of information and communication infrastructure 5G the next generation, neuromarketing and neurobial, neuroimaging consciousness and brain-machine interfaces, biorobots and biochips. 5P medicine and functioning of integrated neural systems through integration and analysis of dynamic hybrid multimodal neural EEG and fMRI information, combined with neuropsychological testing, will allow the geriatrician to manage (prevent and predict), not only healthy aging of Homo sapiens, but also timely diagnosis of osteoporosis and Alzheimer’s disease, treatment start time, definition. Early age (from 40–45 years) diagnosis, treatment and prevention of osteoporosis using tools (technologies) 5P medicine and 5G medical services, will manage the medical, socio-economic problem of our time. Early age diagnosis, treatment and prevention of osteoporosis using tools (technologies) 5P medicine and 5G medical services, allows you to manage a “silent epidemic” (“hidden epidemic”) of the 21st century with the help of non-medicamentous treatments — three multi-paradigm platforms: healthy lifestyle, physical activity, functional nutrition (balanced, healthy, natural). The key to the success of osteoporosis treatment is in a new 5P medicine based on a deep individualized approach and motivation to prevent diseases.

Full Text
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