Abstract
Administration of various 3H-labeled monoterpenes to Catharanthus roseus and Lonicera morrowii demonstrated that secoiridoid glucosides and indole alkaloids of these plants are formed through cyclization of 10-oxoneral or 10-oxogeranial to iridodial followed by further elaboration. This result is contradictory with the report by Kurz et al. which indicated the intermediacy of 9, 10-dihydroxygeraniol and its oxo-derivatives for the biosynthesis of secologanin and indole alkaloids of C. roseus suspension cultures.
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