Abstract
Since 1-thienylisoquinoline derivatives, analogs of papaverine, possessed some analgesic action, three kinds of 1-thienylisoquinoline derivatives were synthesized by the condensation of 2-thienylacetyl chloride with three kinds of amines, α-methyl-β-methoxy-β-(3, 4-methylenedioxyphenyl)-ethylamine, α-methyl-β-(3, 4-methylenedioxyphenyl)-ethylamine, and homoveratrylamine to the corresponding amides which were submitted to the usual isoquinoline cyclization. The physiological action of these compounds are being examined.
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