Abstract
Systematic fractional treatment was carried out on the alkaloids of Berberis Thunbergii DC. (Japanese name ‘Megi’) and the presence of isotetrandrine was proved as the tertiary, non-phenolic, biscoclaurine-type base, besides the alkaloids found to date. Further, presence of a new water-soluble, quaternary base in extremely minute quantity was proved as a picrate of m. p. 217-223°. This is the first example of a presence of non-phenolic, biscoclaurine-type base in the Berberis genus plants.
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