Abstract

Growth inhibition of five kinds of organism of Lactobacteriaceae by 11 kinds compounds structurally related to 2-methyl-4-amino-5-hydroxymethylpyrimidine (OMP) was examined in vitamin-deficient medium. 2-Methyl-4-amino-5-bromome-thylpyrimidine (BMP) showed about the same inhibition as that of OMP but other allied compounds had little or no inhibitory activity. Recovery of BMP inhibition by various vitamins also showed that BMP, the same as OMP, was specifically antagonistic only with thepyridoxine group.

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