Abstract

27 cases of basocellular carcinomas and basosquamous carcinomas of the skin were classified into primordial and differentiated basocellular carcinomas and basosquamous carcinomas and stained for beta-2-microglobulin using the immunoperoxidase technique. All the differentiated basocellular carcinomas and some of the basosquamous carcinomas contained beta-2-microglobulin, but none was found in the primordial basocellular carcinomas. Staining of basal cell tumors for beta-2-microglobulin may be helpful in interpreting adnexoid and epidermoid differentiation in skin tumors.

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