Abstract
The aim of the study was to study the features of the urinary microbiota in patients with urodynamic disorders of the lower urinary tract on the background of decompensated type 2 diabetes.Material and methods. The study was performed on the basis of MCL №10 (Odessa) in 2019-2020. We examined 50 patients with decompensated diabetes mellitus2 with manifestations of urodynamics of the lower urinary tract (main group) and 30 healthy individuals of the same age, examined according to the medical program. The mean age of patients was 42.4 ± 1.1 years. The sample was dominated by women (38 (76.0%) of the main group, 19 (63.3%) of the control group). Among the disorders of urodynamics dominated by manifestations of incontinence. In all patients, fasting blood glucose, glycated hemoglobin HbA1c, glucosuria were determined, and PGS index was calculated.Results. All patients in the main group showed signs of decompensation of diabetes. The average glycemic level was 11.3 ± 1.1 mmol / l, HbA1c content - 8.8 ± 0.9%. The value of PGS in the main group averaged 122 ± 9 units.When assessing the qualitative composition of urine microbiocenoses, it was found that patients of the main group were often identified bacteria of intestinal origin. The total microbial count in the main group averaged 2x107 CFU/ml (cv = 5%), in the control group - 1x104 CFU/ml (cv = 10 %).Conclusions. 1. In patients with diabetes mellitus 2 who have urodynamic disorders, there is both asymptomatic and symptomatic bacteriuria. 2. Urinary microbiota in patients with diabetes mellitus is represented by facultative aerobes and anaerobes. 3. There is a close correlation between the qualitative composition of the intestinal microbiota and the urinary tract in patients with decompensated diabetes mellitus2. 4. To reduce the risk of urinary tract infection in patients with diabetes mellitus, it is advisable to take measures to compensate for the course of the disease, avoid prolonged use of catheters and prophylactic use of uroseptics.
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