운동형태가 제2형 당뇨병환자의 인슐린저항성과 EPO에 미치는 영향

Abstract

The purpose of this study investigated the alteration of insulin resistance and erythropoietin(EPO) as 12week walking training(WT) or circuit weight training(CT) in 14 female patients with type 2 diabetes. The subjects of this study were divided into WT group(N＝7) or CT group(N＝7) randomly. Both in exercise intensity per day, and 3 days per week for total 12weeks. Blood sample of each subject was analyzed with affinity chromatography and radioimmunoassay(RIA) form plasma and serum. The results are as followed. In body composition, weight, BMI, and %Fat levels decreased significantly between before and after 12week exercise in both groups, respectively. Weight and %Fat also are showed the significant differences between the groups after 12week exercise. Insulin, c-peptide, glucose, and HOMA-IR related to insulin resistance decreased significantly before and after 12week exercise in CT groups. HbA1c is showed the significant decrease after 12week exercise in comparsion to before exercise in both group. EPO increased significantly before and after exercise in both groups, respectively. In conclusion, the results of the present study shows that 12week CT more than WT may be the effective exercise improving body composition, insulin resistance, and EPO in female patients with type 2 diabetes. Therefore this study suggests that CT is a beneficial exercise for the improvement of insulin resistance and diabetes complication in type 2 diabetic female patients.