Abstract
A series of pinanylsulfides possessing cis-configuration have been synthesized using addition of 2-mercaptoethanol and thioglycolic acid methyl ether to the double bond of (1S)-(-)-β-pinene. The corresponding sulfoxides and sulfones have been synthesized using the oxidation of sulfides with 3-chlorperbenzoic acid. The thioterpenoids obtained have been tested for antifungal activity. The dynamics of variation of the antimicotic properties in the sulfide - sulfoxide - sulfone series has been investigated.
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