Abstract

Spiculisporic acid, first isolated by Clutterbuck, Raistrick and Rintoul as metabolic product of glucose by Penicillium spiculisporum Lehman, was first shown to be the lactone of γ-hydroxy-β, δ-dicarboxypentadecoic acid but, later, Asano and Kameta decided that it was a lactone of γ-hydroxy-γ, δ-dicarboxypentadecoic acid. Present experiment showed that strain “KT 21” of a rod-shaped bacterium isolated from the soil of a drain near the Kanazawa Medical University, grows excellently in a synthetic medium containing spiculisporic acid as the sole source of carbon and ammoniak as the sole source of nitrogen, at 25°C, and could be cultivated for six generations. For this culture, spiculisporic acid can be replaced by p-hydroxybenzoic acid or phenylacetic acid acid as a source of carbon.

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