Abstract

Alkaloidal component was systematically separated from Stephania japonica MIERS. from Shikoku and Kyushu area. The tertiary non-phenolic bases were separated by alumina chromatography into hasubanonine, protostephanine, two kinds of a base of mp 135° and 165°, thought to be new bases, and an alkaloid of mp 219-223°, assumed to be metaphanine. The tertiary phenolic bases afforded hypoepistephanine, homostephanoline, and a substance of mp 207-208°, thought to be a new base. These are results from the plants collected in Shikoku. The plant from Kyushu yielded, besides eight kinds of bases, epistephanine as the non-phenolic base, The content of various bases according to the locale is shown in Table I.

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